Endocannabinoids
These are molecules made by your body. They’re similar to cannabinoids found in cannabis but they are produced within your own body.
They are called anandamide (AEA) and 2-arachidonoylglyerol (2-AG)
These help keep internal functions running smoothly and your body produces them as needed.
Endocannabinoid receptors
These receptors are found throughout your body and there are billions of them.
There are two main endocannabinoid receptors:
- CB1 receptors, which are mostly found in the brain & central nervous system
- CB2 receptors, which are mostly found in your peripheral nervous system, especially immune cells
The Endocannabinoids we produce can bind to either receptor. The effects that result depend on where the receptor is located and which endocannabinoid it binds to.
For example, endocannabinoids might target CB1 receptors in a spinal nerve to relieve pain. Others might bind to a CB2 receptor in your immune cells to signal that your body’s experiencing inflammation.
Enzymes
Enzymes are responsible for breaking down endocannabinoids once they’ve carried out their function.